Long-term Efficacy of Q-switched 1064 nm Nd-YAG Laser for Treatment of Split-thickness Skin Graft: A Randomized Controlled Trial

Objective: The aim of this study was to investigate the efficacy Q-switched 1064 nm Nd:YAG laser for reducing hyperpigmentation and erythema increasing pliability in skin grafts.Material Methods: This a prospective randomized controlled trial. Half each graft treated with 4 times, other half left untreated collectively used as controls. treatment results were evaluated by clinical photographs, assessment melanin index (MI), (EI), elasticity parameters at baseline 2 weeks after session 1 month final treatment.Results: Ten sites from 10 patients included. Most had lesions lower extremity. After sessions treatment, average non-significantly decreased compared both (p-value=0.232) (p-value=0.770). increased significantly when (p-value=0.039), but (p-value=0.846). EI (p-value=0.432) (p-value=0.164). Conclusion: found be potentially promising modality grafts, reductions only clinically significant.